[HTML][HTML] Expression of VEGF-A/C, VEGF-R2, PDGF-α/β, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma
M Brunner, D Thurnher, J Pammer, S Geleff… - Modern Pathology, 2008 - Elsevier
Merkel cell carcinoma is a rare but very aggressive tumor of the skin. With current treatment
options, Merkel cell carcinoma is associated with a high incidence of recurrence and
metastasis. Targeted anticancer therapies such as receptor tyrosine kinase inhibitors and
antisense oligonucleotides have been found to be a promising new type of treatment for
various types of cancer. To evaluate whether the use of targeted therapies is a possible
treatment option in Merkel cell carcinoma, we determined the expression of the target …
options, Merkel cell carcinoma is associated with a high incidence of recurrence and
metastasis. Targeted anticancer therapies such as receptor tyrosine kinase inhibitors and
antisense oligonucleotides have been found to be a promising new type of treatment for
various types of cancer. To evaluate whether the use of targeted therapies is a possible
treatment option in Merkel cell carcinoma, we determined the expression of the target …