Characterization of a gamma-carboxyglutamic acid-containing protein from bone.
PA Price, AA Otsuka, JW Poser… - Proceedings of the …, 1976 - National Acad Sciences
PA Price, AA Otsuka, JW Poser, J Kristaponis, N Raman
Proceedings of the National Academy of Sciences, 1976•National Acad SciencesA gamma-carboxyglutamic acid-containing protein has been purified from the calcified
tissues of several vertebrates. The presence of three-gamma-carboxyglutamic acid residues
in the bovine protein was established by alkaline hydrolysis and amino acid analysis, a
method based upon studies with synthetic gamma-carboxyglutamic acid. The identity of
gamma-carboxyglutamic acid in the bovine protein was established by mass spectroscopy
on the unknown amino acid isolated from alkaline hydrolysates.
tissues of several vertebrates. The presence of three-gamma-carboxyglutamic acid residues
in the bovine protein was established by alkaline hydrolysis and amino acid analysis, a
method based upon studies with synthetic gamma-carboxyglutamic acid. The identity of
gamma-carboxyglutamic acid in the bovine protein was established by mass spectroscopy
on the unknown amino acid isolated from alkaline hydrolysates.
A gamma-carboxyglutamic acid-containing protein has been purified from the calcified tissues of several vertebrates. The presence of three-gamma-carboxyglutamic acid residues in the bovine protein was established by alkaline hydrolysis and amino acid analysis, a method based upon studies with synthetic gamma-carboxyglutamic acid. The identity of gamma-carboxyglutamic acid in the bovine protein was established by mass spectroscopy on the unknown amino acid isolated from alkaline hydrolysates.
National Acad Sciences