The substance causing renal hypertension
E Braun-Menendez, JC Fasciolo, LF Leloir… - The Journal of …, 1940 - ncbi.nlm.nih.gov
E Braun-Menendez, JC Fasciolo, LF Leloir, JM Muñoz
The Journal of physiology, 1940•ncbi.nlm.nih.govGOLDBLATT, LYNCH, HANZAL & SUMMERVILLE [1934] have shown that chronic arterial
hypertension can be produced bypermanent compression of the renal artery. If the
ischaemic kidney is extirpated or the arterial compression discontinued, the blood pressure
returns to the normal level [Goldblatt et al. 1934; Dicker, 1937; Houssay & Fasciolo, 1937a;
Gold-blatt, 1937; etc.]. Houssay & Fasciolo [1937b] grafted the ischaemic kidneys of dogs
with chronic hypertension into the neck of normal or nephrectomizeddogs. An immediate …
hypertension can be produced bypermanent compression of the renal artery. If the
ischaemic kidney is extirpated or the arterial compression discontinued, the blood pressure
returns to the normal level [Goldblatt et al. 1934; Dicker, 1937; Houssay & Fasciolo, 1937a;
Gold-blatt, 1937; etc.]. Houssay & Fasciolo [1937b] grafted the ischaemic kidneys of dogs
with chronic hypertension into the neck of normal or nephrectomizeddogs. An immediate …
GOLDBLATT, LYNCH, HANZAL & SUMMERVILLE [1934] have shown that chronic arterial hypertension can be produced bypermanent compression of the renal artery. If the ischaemic kidney is extirpated or the arterial compression discontinued, the blood pressure returns to the normal level [Goldblatt et al. 1934; Dicker, 1937; Houssay & Fasciolo, 1937a; Gold-blatt, 1937; etc.].
Houssay & Fasciolo [1937b] grafted the ischaemic kidneys of dogs with chronic hypertension into the neck of normal or nephrectomizeddogs. An immediate increase in blood pressure of 30-70 mm. Hg was observed, whereas no appreciable change was producedby grafting normal kidneys. Bouckaert, Grimson & Heymans [1939] have confirmed these findings which clearly demonstrate that ischaemic kidneys produce a pressor substance.
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