Proliferative activity of intrinsic cell populations in the normal human kidney.
T Nadasdy, Z Laszik, KE Blick… - Journal of the …, 1994 - journals.lww.com
The proliferative activity of various normal human renal cell populations is unknown.
Recently, antibodies to cell proliferation-associated nuclear proteins, such as proliferating
cell nuclear antigen (PCNA) and KI-67, which are applicable to archival paraffin sections,
became available. With antibodies to PCNA and Ki-67 after microwave pretreatment of the
paraffin sections, the proliferation indexes (ratio of positive nuclei with PCNA and Ki-67
antibodies/all nuclei counted x 100, ie percentage of positive cells) of 12 different intrinsic …
Recently, antibodies to cell proliferation-associated nuclear proteins, such as proliferating
cell nuclear antigen (PCNA) and KI-67, which are applicable to archival paraffin sections,
became available. With antibodies to PCNA and Ki-67 after microwave pretreatment of the
paraffin sections, the proliferation indexes (ratio of positive nuclei with PCNA and Ki-67
antibodies/all nuclei counted x 100, ie percentage of positive cells) of 12 different intrinsic …