[CITATION][C] Analysis of clinical, ultrasound and colour flow‐Doppler characteristics in predicting malignancy in follicular thyroid neoplasms

P Trimboli, S Ulisse, M D'Alò, F Solari… - Clinical …, 2008 - Wiley Online Library
P Trimboli, S Ulisse, M D'Alò, F Solari, A Fumarola, M Ruggieri, E De Antoni, A Catania…
Clinical endocrinology, 2008Wiley Online Library
Fine-needle aspiration cytology (FNAC) represents the main diagnostic tool in the
evaluation of thyroid nodules because of its high sensitivity, specificity and accuracy.
However, while FNAC is very reliable in detecting papillary thyroid carcinomas (PTC) and
anaplastic thyroid carcinomas, follicular neoplasms (FN) represent the grey zone in which
cytology cannot discriminate malignant from benign tumours. 1 Consequently, in presence
of nodules cytologically classified as FN, thyroidectomy is usually required and the …
Fine-needle aspiration cytology (FNAC) represents the main diagnostic tool in the evaluation of thyroid nodules because of its high sensitivity, specificity and accuracy. However, while FNAC is very reliable in detecting papillary thyroid carcinomas (PTC) and anaplastic thyroid carcinomas, follicular neoplasms (FN) represent the grey zone in which cytology cannot discriminate malignant from benign tumours. 1 Consequently, in presence of nodules cytologically classified as FN, thyroidectomy is usually required and the histological evaluation reveals that about 80% are benign lesions. Thus, identification of parameters associated with malignancy is needed. In this context, several studies have focused on clinical, ultrasonographic and cytological aspects, with controversial results. 2, 3
We have evaluated the role of clinical, ultrasound (US) and colour flow-Doppler (CFD) characteristics in predicting malignancy in 47 consecutive patients with FN (36 females and 11 males with ages at the time of diagnosis ranging from 20 to 73 years). These did not
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