[HTML][HTML] Dendritic cell subsets in primary and secondary T cell responses at body surfaces
WR Heath, FR Carbone - Nature immunology, 2009 - nature.com
WR Heath, FR Carbone
Nature immunology, 2009•nature.comWe examine the role of dendritic cells subsets in immunity to peripheral infections, with
emphasis on the differences in the regulation of primary and secondary T cell responses to
viruses. Our major focus is on new developments in the understanding of immunity to
infections of the skin and lung, which are crucial entry points for a variety of infectious
pathogens. Initially we describe a diverse network of dendritic cell subsets, but then we
argue for a more generalized model of reduced complexity.
emphasis on the differences in the regulation of primary and secondary T cell responses to
viruses. Our major focus is on new developments in the understanding of immunity to
infections of the skin and lung, which are crucial entry points for a variety of infectious
pathogens. Initially we describe a diverse network of dendritic cell subsets, but then we
argue for a more generalized model of reduced complexity.
Abstract
We examine the role of dendritic cells subsets in immunity to peripheral infections, with emphasis on the differences in the regulation of primary and secondary T cell responses to viruses. Our major focus is on new developments in the understanding of immunity to infections of the skin and lung, which are crucial entry points for a variety of infectious pathogens. Initially we describe a diverse network of dendritic cell subsets, but then we argue for a more generalized model of reduced complexity.
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