[HTML][HTML] Cross-talk between P2X4 and γ-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse

YH Jo, E Donier, A Martinez, M Garret, E Toulmé… - Journal of Biological …, 2011 - ASBMB
The essence of neuronal function is to generate outputs in response to synaptic potentials.
Synaptic integration at postsynaptic sites determines neuronal outputs in the CNS. Using
immunohistochemical and electrophysiological approaches, we first reveal that
steroidogenic factor 1 (SF-1) green fluorescent protein (GFP)-positive neurons in the
ventromedial nucleus of the hypothalamus express P2X4 subunits that are activated by
exogenous ATP. Increased membrane expression of P2X4 channels by using a peptide …