Intracoronary abciximab and aspiration thrombectomy in patients with large anterior myocardial infarction: the INFUSE-AMI randomized trial

GW Stone, A Maehara, B Witzenbichler, J Godlewski… - Jama, 2012 - jamanetwork.com
Context Thrombus embolization during percutaneous coronary intervention (PCI) in ST-
segment elevation myocardial infarction (STEMI) is common and results in suboptimal
myocardial perfusion and increased infarct size. Two strategies proposed to reduce distal
embolization and improve outcomes after primary PCI are bolus intracoronary abciximab
and manual aspiration thrombectomy. Objective To determine whether bolus intracoronary
abciximab, manual aspiration thrombectomy, or both reduce infarct size in high-risk patients …