Diamond Blackfan anemia treatment: past, present, and future
A Narla, A Vlachos, DG Nathan - Seminars in hematology, 2011 - Elsevier
Despite significant improvements in our understanding of the pathophysiology of Diamond
Blackfan anemia (DBA), there have been few advances in therapy. The cornerstones of
treatment remain corticosteroids, chronic red blood cell transfusions, and hematopoietic
stem cell transplantation, each of which is fraught with complications. In this article, we will
review the history of therapies that have been offered to patients with DBA, summarize the
current standard of care, including management of side effects, and discuss novel …
Blackfan anemia (DBA), there have been few advances in therapy. The cornerstones of
treatment remain corticosteroids, chronic red blood cell transfusions, and hematopoietic
stem cell transplantation, each of which is fraught with complications. In this article, we will
review the history of therapies that have been offered to patients with DBA, summarize the
current standard of care, including management of side effects, and discuss novel …