ADAR gene family and A-to-I RNA editing: diverse roles in posttranscriptional gene regulation
L Valente, K Nishikura - Progress in nucleic acid research and molecular …, 2005 - Elsevier
Publisher Summary The biological process of A-to-I RNA editing mediated by ADAR is
discussed with new directions on potentially novel targets, including the widely expressed
Alu retrotransposable elements found in noncoding regions of mRNA. Many events take
place after the de novo synthesis of an RNA transcript, leading to alterations from its gene-
encoded origin. In addition to posttranslational modification, which occurs after the
production of the polypeptide chain, RNA can be modified in several ways as to vary the …
discussed with new directions on potentially novel targets, including the widely expressed
Alu retrotransposable elements found in noncoding regions of mRNA. Many events take
place after the de novo synthesis of an RNA transcript, leading to alterations from its gene-
encoded origin. In addition to posttranslational modification, which occurs after the
production of the polypeptide chain, RNA can be modified in several ways as to vary the …