Homotransplanted canine livers can survive in recipient dogs for as long as 3 weeks. 10, 11
Evaluation of liver function and other tissue metabolism can be made during this time.
Studies of this kind may lead to a better understanding of the homograft rejection
mechanism. Previous histological and biochemical studies in dogs following total
homotransplantation of the liver have shown a marked proliferative cellular response in the
organs and a progressive obstructive jaundice pattern in the blood. Total serum protein and …