[HTML][HTML] Heart specific expression of mouse BMP-10 a novel member of the TGF-β superfamily
H Neuhaus, V Rosen, RS Thies - Mechanisms of development, 1999 - Elsevier
H Neuhaus, V Rosen, RS Thies
Mechanisms of development, 1999•ElsevierHere we report the cloning and expression of murine BMP-10, a novel member of the TGF-β
superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 dpc and is restricted to
the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the
common ventricular chamber and to the bulbus cordis region. After 12.5 dpc, additional BMP-
10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays
an important role in trabeculation of the embryonic heart.
superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 dpc and is restricted to
the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the
common ventricular chamber and to the bulbus cordis region. After 12.5 dpc, additional BMP-
10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays
an important role in trabeculation of the embryonic heart.
Here we report the cloning and expression of murine BMP-10, a novel member of the TGF-β superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 d.p.c. and is restricted to the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the common ventricular chamber and to the bulbus cordis region. After 12.5 d.p.c., additional BMP-10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays an important role in trabeculation of the embryonic heart.
Elsevier