Expression of islet-specific microRNAs during human pancreatic development

MV Joglekar, VM Joglekar, AA Hardikar - Gene Expression Patterns, 2009 - Elsevier
During pancreatic islet development, sequential changes in gene expression are known to
be necessary for efficient differentiation and function of the endocrine pancreas. Several
studies till now have demonstrated that microRNAs (miRNAs), which regulate translation of
gene transcripts, influence gene expression cascades involved in pancreas development.
Some of these miRNAs; miR-7 and miR-375 have been known to be expressed at high
levels in pancreas and are also known to be involved in Zebrafish pancreas development as …