Plasmodium falciparum: studies on mature exoerythrocytic forms in the liver of the chimpanzee, Pan troglodytes
JFGM Meis, T Ponnudurai, B Mons, A van Belkum… - Experimental …, 1990 - Elsevier
Mature exoerythrocytic forms (EEF) of Plasmodium falciparum from the chimpanzee were
examined by light-and transmission electron microscopy from a liver biopsy taken on Day 6
after sporozoite inoculation. Infectivity of the sporozoites obtained from whole mosquitoes
which were membrane fed on cultured gametocytes was about 4–6%. In comparison,
salivary gland sporozoites added to human hepatocytes in vitro had only a developmental
percentage of 0.02 to 0.05% at Day 5. The EEF found in the liver biopsy were not all at the …
examined by light-and transmission electron microscopy from a liver biopsy taken on Day 6
after sporozoite inoculation. Infectivity of the sporozoites obtained from whole mosquitoes
which were membrane fed on cultured gametocytes was about 4–6%. In comparison,
salivary gland sporozoites added to human hepatocytes in vitro had only a developmental
percentage of 0.02 to 0.05% at Day 5. The EEF found in the liver biopsy were not all at the …