The neurocristopathies: a unifying concept of disease arising in neural crest maldevelopment

RP Bolande - Human pathology, 1974 - Elsevier
Pheochromocytoma, neuroblastoma, neurofibromatosis, medullary carcinoma of the thyroid,
carcinoid tumors, Hirschsprung's disease, and nonchromaffin paragangliomas are
discussed and analysed in terms of their proposed neural crest origins. Combinations and
permutations of these entities form discrete syndromes, all of which tend to be
embryogenetically related as the neurocristopathies. Other peculiar interrelationships are
shown, emphasizing their common neuroectodermal origin. The wide distribution and …