Progressive polyploidy in mouse liver following repeated hepatectomy
VM Faktor, IV Uryvaeva - Tsitologiia, 1975 - europepmc.org
VM Faktor, IV Uryvaeva
Tsitologiia, 1975•europepmc.orgMouse liver regeneration after partial hepatectomy results in sharp changes of ploidy
classes towards the increase of high ploidy cells and the decrease low ploidy ones. These
changes retain during three months. Each following partial hepatectomy (till 3 times)
intensifies the hepatocyte polyploidy with appearance of cells with 32--64 ploidy nuclei. The
cell polyploidization stimulated by repeated regenerations is similar to that observed in
normal postnatal liver growth.
classes towards the increase of high ploidy cells and the decrease low ploidy ones. These
changes retain during three months. Each following partial hepatectomy (till 3 times)
intensifies the hepatocyte polyploidy with appearance of cells with 32--64 ploidy nuclei. The
cell polyploidization stimulated by repeated regenerations is similar to that observed in
normal postnatal liver growth.
Mouse liver regeneration after partial hepatectomy results in sharp changes of ploidy classes towards the increase of high ploidy cells and the decrease low ploidy ones. These changes retain during three months. Each following partial hepatectomy (till 3 times) intensifies the hepatocyte polyploidy with appearance of cells with 32--64 ploidy nuclei. The cell polyploidization stimulated by repeated regenerations is similar to that observed in normal postnatal liver growth.
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