Cross-sectional and longitudinal studies were performed in a rural population living in The
Gambia to examine the relationship between several in vitro assays of the host immune
response to asexual stages of Plasmodium falciparum and protection from malaria in vivo.
Assays included an enzyme-linked immunosorbent assay for antibodies to schizont
antigens; an indirect immunofluorescence assay for total antiblood-stage antibodies; an
immunofluorescence assay on glutaraldehyde-fixed parasites to detect antibodies to antigen …