Increasing adipocyte size as well as numbers is important in the development of obesity and
type 2 diabetes, with adipocytes being generated from mesenchymal precursor cells. This
process includes the determination of mesenchymal stem cells (MSC) into preadipocytes
(PA) and the differentiation of PA into mature fat cells. Although the process of differentiation
has been highly investigated, the determination in humans is poorly understood. In this
study, we compared human MSC and human committed PA on a cellular and molecular …