Quantitation of maximal bactericidal capability in human neutrophils
CC Clawson, JE Repine - The Journal of Laboratory and …, 1976 - translationalres.com
The quantitative capacity of normal human neutrophils to ingest and kill increasing multiples
of bacteria up to a level of saturation was evaluated. The in vitro system, a modification of
classic bactericidal assay, employed carefully controlled ratios of bacteria per neutrophil
between 1.25 and 400: 1 to stress neutrophil function. Morphologic examination and
measurement of bacterial survival by quantitative plate culturing indicated that at a
challenge of about 100 Staphylococcus aureus per neutrophil bactericidal activity reached …
of bacteria up to a level of saturation was evaluated. The in vitro system, a modification of
classic bactericidal assay, employed carefully controlled ratios of bacteria per neutrophil
between 1.25 and 400: 1 to stress neutrophil function. Morphologic examination and
measurement of bacterial survival by quantitative plate culturing indicated that at a
challenge of about 100 Staphylococcus aureus per neutrophil bactericidal activity reached …