Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal …
RH Zetterström, R Williams, T Perlmann… - Molecular brain research, 1996 - Elsevier
Nurr1 and NGFI-B are closely related orphan members of the steroid-thyroid hormone
receptor family involved in immediate early responses to stimuli such as growth factors. In-
situ hybridization in the developing and adult mouse and rat demonstrated Nurr1 mRNA in
several regions during early central nervous system (CNS) development. Expression
persisted through the pre-and postnatal periods and was also found in several areas in the
adult CNS. Positive areas include the olfactory bulb, parts of the cortex, the hippocampal …
receptor family involved in immediate early responses to stimuli such as growth factors. In-
situ hybridization in the developing and adult mouse and rat demonstrated Nurr1 mRNA in
several regions during early central nervous system (CNS) development. Expression
persisted through the pre-and postnatal periods and was also found in several areas in the
adult CNS. Positive areas include the olfactory bulb, parts of the cortex, the hippocampal …