Cord blood cytokines and acute lower respiratory illnesses in the first year of life

NP Ly, SL Rifas-Shiman, AA Litonjua… - …, 2007 - publications.aap.org
OBJECTIVES. Little is known about the relation between cytokine profile at birth and acute
lower respiratory illnesses in the first year of life. The purpose of this work was to examine
the relation between cytokine secretions by cord blood mononuclear cells and acute lower
respiratory illness in a birth cohort of 297 children. METHODS. Cord blood mononuclear
cells were isolated, and secretion of interferon-γ, interleukin-13, interleukin-10, and tumor
necrosis factor-α at baseline and in response to allergens (Blatella germanica 2 and …