Obstructive sleep apnea syndrome in a patient with medulloblastoma

G Greenough, M Sateia, CE Fadul - Neuro-oncology, 1999 - academic.oup.com
G Greenough, M Sateia, CE Fadul
Neuro-oncology, 1999academic.oup.com
We present one adult patient with medulloblastoma who developed polysomnographically
documented obstructive sleep apnea after posterior fossa surgery. The sleep apnea
worsened in conjunction with clinical and imaging-con-firmed neoplastic progression and
clinically improved after craniospinal radiation therapy. Medulloblastoma or its surgical
treatment has never before been implicated in a sleep-related breathing disorder. We
discuss possible mechanisms for its occurrence and management implications.
Abstract
We present one adult patient with medulloblastoma who developed polysomnographically documented obstructive sleep apnea after posterior fossa surgery. The sleep apnea worsened in conjunction with clinical and imaging-con-firmed neoplastic progression and clinically improved after craniospinal radiation therapy. Medulloblastoma or its surgical treatment has never before been implicated in a sleep-related breathing disorder. We discuss possible mechanisms for its occurrence and management implications.
Oxford University Press