Simple, inexpensive method for automating tissue microarray production provides enhanced microarray reproducibility

BE Matysiak, T Brodzeller, S Buck… - Applied …, 2003 - journals.lww.com
Tissue microarrays are a novel technology with the potential to impact cancer research by
reducing the time, materials, and costs related to specimen-based marker validation. The
process uses small cores of specimen tissue for molecular studies, maximizing the quantity
of specimens that can be analyzed on a single slide and the results that can be obtained
from a single antibody study. However, this process can be tedious and requires a
significant time commitment for array production, particularly for the hand-produced tissue …