Immature dendritic cells (Dcs) are characterised by high antigen uptake ability and poor T-
cell stimulatory function. In contrast, mature DCs have a high stimulatory function and poor
antigen uptake ability. Inflammatory stimuli induce DC maturation and migration from
nonlymphoid tissues to lymphoid organs. We investigated the effect of lipopolysaccharide
(LPS) on DC antigen uptake and migratory function at early and late stimulation time points.
We observed that the transition from the immature to the mature state is not a progressive …