Noninvasive imaging should facilitate the analysis of changes in experimental tumors and
metastases-expressing photoproteins and result in improved data consistency and
experimental animal welfare. We analyzed quantitative aspects of noninvasive imaging of
luciferase-labeled tumors by comparing the efficiency of noninvasive light detection with in
vitro quantification of luciferase activity. An intensified charge coupled device video camera
was used to noninvasively image luciferase-expressing human prostate tumors and …