Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis
S Nischwitz, S Cepok, A Kroner, C Wolf, M Knop… - Journal of …, 2010 - Elsevier
In a genome wide association study consisting of 592 German multiple sclerosis (MS)
patients and 825 controls we were able to replicate the association of the HLA region with
MS independently of previous case control studies. No SNPs outside the HLA region
reached a genome wide level of significance. Nevertheless, we found suggestive evidence
for an association of MS with variants in two new genes, the VAV2 gene and the gene for
ZNF433.
patients and 825 controls we were able to replicate the association of the HLA region with
MS independently of previous case control studies. No SNPs outside the HLA region
reached a genome wide level of significance. Nevertheless, we found suggestive evidence
for an association of MS with variants in two new genes, the VAV2 gene and the gene for
ZNF433.