Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis
J Booss, MM Esiri, WW Tourtellotte… - Journal of the neurological …, 1983 - Elsevier
In an analysis of pooled data, we have found that cytotoxic-suppressor T cells outnumber the
helper-inducer subset and also the population of cells bearing the pan-T cell marker in
specimens of CNS from patients dying with MS (Booss et al. 1983). In the present study of
individual data, we have reviewed the case histories to determine if these findings were
consistent in various clinical settings. Variables examined included disease duration, tempo
of evolution, immunosuppressive therapy, and other potentially immunomodulating features …
helper-inducer subset and also the population of cells bearing the pan-T cell marker in
specimens of CNS from patients dying with MS (Booss et al. 1983). In the present study of
individual data, we have reviewed the case histories to determine if these findings were
consistent in various clinical settings. Variables examined included disease duration, tempo
of evolution, immunosuppressive therapy, and other potentially immunomodulating features …