Reductive evolution of resident genomes
SGE Andersson, CG Kurland - Trends in microbiology, 1998 - cell.com
SGE Andersson, CG Kurland
Trends in microbiology, 1998•cell.comSmall, asexual populations are expected to accumulate deleterious substitutions and
deletions in an irreversible manner, which in the long-term will lead to mutational meltdown
and genome decay. Here, we discuss the influence of such reductive processes on the
evolution of genomes that replicate within the domain of a host genome.
deletions in an irreversible manner, which in the long-term will lead to mutational meltdown
and genome decay. Here, we discuss the influence of such reductive processes on the
evolution of genomes that replicate within the domain of a host genome.
Abstract
Small, asexual populations are expected to accumulate deleterious substitutions and deletions in an irreversible manner, which in the long-term will lead to mutational meltdown and genome decay. Here, we discuss the influence of such reductive processes on the evolution of genomes that replicate within the domain of a host genome.
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