Optic nerve damage in human glaucoma: II. The site of injury and susceptibility to damage
HA Quigley, EM Addicks, WR Green… - Archives of …, 1981 - jamanetwork.com
• We examined the histologic structure of the optic nerve head in 15 eyes of nine persons
with a known glaucoma history. All had been seeing eyes, varying from normal visual acuity
and visual field to advanced glaucoma damage. The site of damage to nerve fibers is the
scleral lamina cribrosa, where there is local blockage of axonal transport. Early cup size
increase prior to definite field loss results from loss of nerve fibers, not from damage to
astrocytic glial cells of the nerve head. No selective damage to nerve head capillaries is …
with a known glaucoma history. All had been seeing eyes, varying from normal visual acuity
and visual field to advanced glaucoma damage. The site of damage to nerve fibers is the
scleral lamina cribrosa, where there is local blockage of axonal transport. Early cup size
increase prior to definite field loss results from loss of nerve fibers, not from damage to
astrocytic glial cells of the nerve head. No selective damage to nerve head capillaries is …