T lymphocytes require Ca²⁺ entry though the plasma membrane for their activation and function. Recently, several routes for Ca²⁺ entry through the T‐cell plasma membrane after activation have been described. These include calcium release‐activated channels (CRAC), transient receptor potential (TRP) channels, and inositol‐1,4,5‐trisphosphate receptors (IP₃Rs). Herein we review the emergence of a fourth new route for Ca²⁺ entry, composed of Ca_v channels (also known as L‐type voltage‐gated calcium channels) and the scaffold protein AHNAK1 (AHNAK/desmoyokin). Both helper (CD4⁺) and killer (CD8⁺) T cells express high levels of Ca_v1 α1 subunits (α1S, α1C, α1D, and α1F) and AHNAK1 after their differentiation and require these molecules for Ca²⁺ entry during an immune response. In this article, we describe the observations and open questions that ultimately suggest the involvement of multiple consecutive routes for Ca²⁺ entry into lymphocytes, one of which may be mediated by Ca_v channels and AHNAK1.