[HTML][HTML] Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene: structure, expression, and function in the formation of the tracheal system
K Kamimura, M Fujise, F Villa, S Izumi… - Journal of Biological …, 2001 - ASBMB
Heparan sulfate, one of the most abundant components of the cell surface and the
extracellular matrix, is involved in a variety of biological processes such as growth factor
signaling, cell adhesion, and enzymatic catalysis. The heparan sulfate chains have
markedly heterogeneous structures in which distinct sequences of sulfate groups determine
specific binding properties. Sulfation at each different position of heparan sulfate is
catalyzed by distinct enzymes, sulfotransferases. In this study, we identified and …
extracellular matrix, is involved in a variety of biological processes such as growth factor
signaling, cell adhesion, and enzymatic catalysis. The heparan sulfate chains have
markedly heterogeneous structures in which distinct sequences of sulfate groups determine
specific binding properties. Sulfation at each different position of heparan sulfate is
catalyzed by distinct enzymes, sulfotransferases. In this study, we identified and …