[HTML][HTML] Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration
C Mitchell, M Nivison, LF Jackson, R Fox… - Journal of Biological …, 2005 - ASBMB
The mechanisms that regulate the transition between the initial priming phase and DNA
replication in liver regeneration are poorly understood. To study this transition, we compared
events occurring after standard two-thirds partial hepatectomy, which elicits full
regeneration, with response to a reduced hepatectomy, one-third partial hepatectomy
(1/3PH), which leads to little DNA replication. Although the initial response to partial
hepatectomy at the priming phase appeared to be similar between the two procedures, cell …
replication in liver regeneration are poorly understood. To study this transition, we compared
events occurring after standard two-thirds partial hepatectomy, which elicits full
regeneration, with response to a reduced hepatectomy, one-third partial hepatectomy
(1/3PH), which leads to little DNA replication. Although the initial response to partial
hepatectomy at the priming phase appeared to be similar between the two procedures, cell …