[HTML][HTML] Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
LR Treviño, N Shimasaki, W Yang… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
LR Treviño, N Shimasaki, W Yang, JC Panetta, C Cheng, D Pei, D Chan, A Sparreboom…
Journal of Clinical Oncology, 2009•ncbi.nlm.nih.govGermline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With
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Methotrexate Pharmacokinetics and Clinical Effects - PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Search PMC Full-Text Archive Search in PMC Advanced Search User Guide Journal List J
Clin Oncol PMC2793040 Other Formats PDF (224K) Actions Cite Collections Share Permalink
Copy RESOURCES Similar articles Cited by other articles Links to NCBI Databases Journal …
Abstract
Purpose
Methotrexate plasma concentration is related to its clinical effects. Our aim was to identify the genetic basis of interindividual variability in methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia (ALL).
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