The human multidrug resistance protein 3 (MRP3, symbol ABCC3) is an ATP-binding
cassette transporter that mediates the efflux of organic anions, including lipophilic
substances conjugated with glucuronate, sulphate or glutathione, across the basolateral
membrane of polarized cells (eg hepatocytes) into blood. Genetic variants of MRP3 may
affect the transport of these substances out of cells. The aims of this study were:(i) to identify
MRP3 polymorphisms;(ii) to functionally characterize one relatively frequent MRP3 …