New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8

ZE Karanjawala, PB Illei, R Ashfaq… - The American journal …, 2008 - journals.lww.com
Background New markers to distinguish benign reactive glands from infiltrating ductal
adenocarcinoma of the pancreas are needed. Design The gene expression patterns of 24
surgically resected primary infiltrating ductal adenocarcinomas of the pancreas were
compared with 18 non-neoplastic samples using the Affymetrix U133 Plus 2.0 Arrays and
the Gene Logic GeneExpress Software System. Gene fragments from 4 genes (annexin A8,
claudin 18, CXCL5, and S100 A2) were selected from the fragments found to be highly …