Motor hyperactivity caused by a deficit in dopaminergic neurons and the effects of endocrine disruptors: a study inspired by the physiological roles of PACAP in the …
Y Masuo, M Morita, S Oka, M Ishido - Regulatory peptides, 2004 - Elsevier
Recent studies have revealed that the pituitary adenylate cyclase-activating polypeptide
(PACAP) might act as a psychostimulant. Here we investigated the mechanisms underlying
motor hyperactivity in patients with pervasive developmental disorders, such as autism, and
attention-deficit hyperactivity disorder (ADHD). We studied the effects of intracisternal
administration of 6-hydroxydopamine (6-OHDA) or endocrine disruptors (EDs) on
spontaneous motor activity (SMA) and multiple gene expression in neonatal rats. Treatment …
(PACAP) might act as a psychostimulant. Here we investigated the mechanisms underlying
motor hyperactivity in patients with pervasive developmental disorders, such as autism, and
attention-deficit hyperactivity disorder (ADHD). We studied the effects of intracisternal
administration of 6-hydroxydopamine (6-OHDA) or endocrine disruptors (EDs) on
spontaneous motor activity (SMA) and multiple gene expression in neonatal rats. Treatment …