[HTML][HTML] A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase
Y Wang, MS Goligorsky, M Lin, JN Wilcox… - Journal of Biological …, 1997 - ASBMB
mRNA diversity represents a major theme of neuronal nitric-oxide synthase (nNOS) gene
expression in somatic cells/tissues. Given that gonads often express unique and biologically
informative variants of complex genes, we determined whether unique variants of nNOS are
expressed in the testis. Analysis of cDNA clones isolated from human testis identified a
novel, testis-specific nNOS (TnNOS) mRNA transcript. A predicted 3294-base pair open
reading frame encodes an NH 2-terminal truncated protein of 1098 amino acids …
expression in somatic cells/tissues. Given that gonads often express unique and biologically
informative variants of complex genes, we determined whether unique variants of nNOS are
expressed in the testis. Analysis of cDNA clones isolated from human testis identified a
novel, testis-specific nNOS (TnNOS) mRNA transcript. A predicted 3294-base pair open
reading frame encodes an NH 2-terminal truncated protein of 1098 amino acids …