[HTML][HTML] Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine
H Lapillonne, L Kobari, C Mazurier, P Tropel… - …, 2010 - ncbi.nlm.nih.gov
H Lapillonne, L Kobari, C Mazurier, P Tropel, MC Giarratana, I Zanella-Cleon, L Kiger…
Haematologica, 2010•ncbi.nlm.nih.govBackground Ex vivo manufacture of red blood cells from stem cells is a potential means to
ensure an adequate and safe supply of blood cell products. Advances in somatic cell
reprogramming of human induced pluripotent stem cells have opened the door to
generating specific cells for cell therapy. Human induced pluripotent stem cells represent a
potentially unlimited source of stem cells for erythroid generation for transfusion medicine.
ensure an adequate and safe supply of blood cell products. Advances in somatic cell
reprogramming of human induced pluripotent stem cells have opened the door to
generating specific cells for cell therapy. Human induced pluripotent stem cells represent a
potentially unlimited source of stem cells for erythroid generation for transfusion medicine.
Abstract
Background
Ex vivo manufacture of red blood cells from stem cells is a potential means to ensure an adequate and safe supply of blood cell products. Advances in somatic cell reprogramming of human induced pluripotent stem cells have opened the door to generating specific cells for cell therapy. Human induced pluripotent stem cells represent a potentially unlimited source of stem cells for erythroid generation for transfusion medicine.
ncbi.nlm.nih.gov