Endothelial progenitor cells

AY Khakoo, T Finkel - Annu. Rev. Med., 2005 - annualreviews.org
AY Khakoo, T Finkel
Annu. Rev. Med., 2005annualreviews.org
Endothelial progenitor cells are a circulating, bone marrow–derived cell population that
appears to participate in both vasculogenesis and vascular homeostasis. Questions persist
regarding their functional characteristics, as well as the precise panel of cell surface markers
that uniquely define this newly described progenitor cell population. We review experimental
results obtained from both animal studies and recent clinical trials that suggest this cell type
may have tremendous therapeutic potential for a wide range of human diseases.
Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.
Annual Reviews