[PDF][PDF] Brown fat biology and thermogenesis
D Richard, F Picard - Front Biosci, 2011 - article.imrpress.com
D Richard, F Picard
Front Biosci, 2011•article.imrpress.comIntroduction: overview of brown fat 3. The biology of the brown adipocyte 3.1. PPARγ and
PGC1α are key regulators of brown fat cell differentiation 3.2. Brown adipocytes in classical
BAT depots emerge from dermomyotome cells 3.3. PRDM16 induces brown fat from a
myoblastic lineage 3.4. UCP1-expressing cells in WAT could emerge from varied origins 4.
UCP1 4.1. UCP1 has evolved as the only thermogenic UCP 4.2. UCPI confers BAT its
extraordinary thermogenic power 4.3. UCP1 is a nucleotide-sensitive metabolic uncoupler …
PGC1α are key regulators of brown fat cell differentiation 3.2. Brown adipocytes in classical
BAT depots emerge from dermomyotome cells 3.3. PRDM16 induces brown fat from a
myoblastic lineage 3.4. UCP1-expressing cells in WAT could emerge from varied origins 4.
UCP1 4.1. UCP1 has evolved as the only thermogenic UCP 4.2. UCPI confers BAT its
extraordinary thermogenic power 4.3. UCP1 is a nucleotide-sensitive metabolic uncoupler …
Abstract
Introduction: overview of brown fat 3. The biology of the brown adipocyte 3.1. PPARγ and PGC1α are key regulators of brown fat cell differentiation 3.2. Brown adipocytes in classical BAT depots emerge from dermomyotome cells 3.3. PRDM16 induces brown fat from a myoblastic lineage 3.4. UCP1-expressing cells in WAT could emerge from varied origins 4. UCP1
4.1. UCP1 has evolved as the only thermogenic UCP 4.2. UCPI confers BAT its extraordinary thermogenic power 4.3. UCP1 is a nucleotide-sensitive metabolic uncoupler 4.4. UCP1 expression is controlled at the transcriptional level 5. BAT, energy balance regulation and obesity 5.1. SNS-mediated thermogenesis is a determinant of energy expenditure 6. The control of SNS-mediated BAT thermogenesis 6.1. The preoptic area (POA), dorsomedial hypothalamus (DMH), rostral ventromedial medulla (RVM) govern thermoregulatory thermogenesis
article.imrpress.com