Low-density lipoprotein (LDL) cholesterol is an established risk factor for coronary heart
disease (CHD). In the presence of oxidative stress LDL particles can become oxidized to
form a lipoprotein species that is particularly atherogenic. Indeed, oxidized LDL (oxLDL) is
pro-inflammatory, it can cause endothelial dysfunction and it readily accumulates within the
arterial wall. Several factors may influence the susceptibility of LDL to oxidation, including its
size and composition, and the presence of endogenous antioxidant compounds, such as α …