Platelet adhesion and arteriolar dilation in the photothrombosis: observation with the rat closed cranial and spinal windows
M Ishikawa, E Sekizuka, C Oshio, S Sato… - Journal of the …, 2002 - Elsevier
The mechanism of cerebral infarction, in which thrombus formation and platelet–
endothelium interaction play an important part, have not yet been clearly elucidated in vivo.
The aim of this study was to observe rolling and adherent platelets and to analyze adherent
leukocytes and vessel diameter change in vivo using a photothrombotic vessel occlusion
model. A photothrombosis, which is mediated by free radicals, was induced in male Wistar
rats in the presence of a photosensitizing dye (Photofrin II) and exposure to a filtered light …
endothelium interaction play an important part, have not yet been clearly elucidated in vivo.
The aim of this study was to observe rolling and adherent platelets and to analyze adherent
leukocytes and vessel diameter change in vivo using a photothrombotic vessel occlusion
model. A photothrombosis, which is mediated by free radicals, was induced in male Wistar
rats in the presence of a photosensitizing dye (Photofrin II) and exposure to a filtered light …