Myeloid-derived suppressor cells in human cancer
S Nagaraj, DI Gabrilovich - The Cancer Journal, 2010 - journals.lww.com
S Nagaraj, DI Gabrilovich
The Cancer Journal, 2010•journals.lww.comMyeloid-derived suppressor cells are one of the major factors responsible for immune
suppression in cancer. They also contribute to limited efficacy of current vaccination
strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing
primarily on the studies in cancer patients and current and future therapeutic options
targeting these cells.
suppression in cancer. They also contribute to limited efficacy of current vaccination
strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing
primarily on the studies in cancer patients and current and future therapeutic options
targeting these cells.
Abstract
Myeloid-derived suppressor cells are one of the major factors responsible for immune suppression in cancer. They also contribute to limited efficacy of current vaccination strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing primarily on the studies in cancer patients and current and future therapeutic options targeting these cells.
Lippincott Williams & Wilkins