Publisher Summary This chapter discusses the studies of the control of gluconeogenesis.
Although the data presented are almost exclusively derived from studies in the isolated
perfused rat liver, an attempt has been made to relate them to results obtained in vivo and to
relevant investigations in other tissues. The findings indicate that variations in substrate
supply are important in the physiological regulation of gluconeogenesis and that insulin,
glucagon, glucocorticoids, and catecholamines exert important effects at the hepatic level …