The subventricular zone (SVZ) is known to be the major source of neural stem cells in the
adult brain. In rodents and nonhuman primates, many neuroblasts generated in the SVZ
migrate in chains along the rostral migratory stream (RMS) to populate the olfactory bulb
(OB) with new granular and periglomerular interneurons. In order to know if such a
phenomenon exists in the adult human brain, we applied single and double immunostaining
procedures to olfactory bulbs obtained following brain necropsy in normal adult human …