Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States
F Xu, MR Sternberg, BJ Kottiri, GM McQuillan, FK Lee… - Jama, 2006 - jamanetwork.com
ContextHerpes simplex virus type 1 (HSV-1) and type 2 are common infections worldwide.
Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes and is almost
always sexually transmitted. In contrast, HSV-1 is usually transmitted during childhood via
nonsexual contacts. Preexisting HSV-1 antibodies can alleviate clinical manifestations of
subsequently acquired HSV-2. Furthermore, HSV-1 has become an important cause of
genital herpes in some developed countries. ObjectiveTo examine trends in HSV-1 and HSV …
Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes and is almost
always sexually transmitted. In contrast, HSV-1 is usually transmitted during childhood via
nonsexual contacts. Preexisting HSV-1 antibodies can alleviate clinical manifestations of
subsequently acquired HSV-2. Furthermore, HSV-1 has become an important cause of
genital herpes in some developed countries. ObjectiveTo examine trends in HSV-1 and HSV …