The extent of biliary proliferation in liver biopsies from patients with biliary atresia at portoenterostomy is associated with the postoperative prognosis
JL Santos, CO Kieling, L Meurer, S Vieira… - Journal of Pediatric …, 2009 - Elsevier
BACKGROUND/PURPOSE: In biliary atresia (BA), a derangement in the biliary system
remains, despite portoenterostomy performance. Many factors can influence the disease
progression rate. This study aimed to analyze the association between biliary proliferation
extent in biopsies from BA patients and postoperative prognosis. METHODS: Biliary
proliferation was evaluated by a morphometric analysis of the cytokeratin 7 positivity
percentage (PCK7) in wedge liver biopsies from 47 BA patients. The extent of fibrosis was …
remains, despite portoenterostomy performance. Many factors can influence the disease
progression rate. This study aimed to analyze the association between biliary proliferation
extent in biopsies from BA patients and postoperative prognosis. METHODS: Biliary
proliferation was evaluated by a morphometric analysis of the cytokeratin 7 positivity
percentage (PCK7) in wedge liver biopsies from 47 BA patients. The extent of fibrosis was …