Recent advances in the pathophysiology of ischemic acute renal failure

JV Bonventre, JM Weinberg - Journal of the American Society of …, 2003 - journals.lww.com
As covered in the preceding sections, acute renal failure (ARF) is a syndrome associated
with high mortality in humans. Current therapy is limited to supportive measures and
preventive strategies, none of which have been definitively shown to alter mortality. Ischemic
ARF is often associated with multiple organ failure and sepsis. Despite the complexity of
multi-organ illness, the presence of ARF independently carries a marked increase in
mortality (1). This review is a brief treatment of our current understanding of the …