Drosophila larval NMJ dissection
JR Brent, KM Werner, BD McCabe - JoVE (Journal of Visualized …, 2009 - jove.com
The Drosophila neuromuscular junction (NMJ) is an established model system used for the
study of synaptic development and plasticity. The widespread use of the Drosophila motor
system is due to its high accessibility. It can be analyzed with single-cell resolution. There
are 30 muscles per hemisegment whose arrangement within the peripheral body wall are
known. A total of 35 motor neurons attach to these muscles in a pattern that has high fidelity.
Using molecular biology and genetics, one can create transgenic animals or mutants. Then …
study of synaptic development and plasticity. The widespread use of the Drosophila motor
system is due to its high accessibility. It can be analyzed with single-cell resolution. There
are 30 muscles per hemisegment whose arrangement within the peripheral body wall are
known. A total of 35 motor neurons attach to these muscles in a pattern that has high fidelity.
Using molecular biology and genetics, one can create transgenic animals or mutants. Then …