More than 50 years after Ogdeon Bruton's discovery of congenital agammaglobulinemia,
human primary immunodeficiencies (PIDs) continue to unravel novel molecular and cellular
mechanisms that govern development and function of the human immune system. This
report provides the updated classification of PIDs that has been compiled by the
International Union of Immunological Societies Expert Committee on Primary
Immunodeficiencies after its biannual meeting in Dublin, Ireland, in June 2009. Since the …